Alfons Verbruggen Selected Research

pamoic acid

7/2010	Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography.
6/2009	Molecular imaging of cell death.
11/2007	Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis.

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Alfons Verbruggen Research Topics

Disease

22	Neoplasms (Cancer) 12/2017 - 03/2006
22	Necrosis 05/2015 - 05/2002
4	Neuroinflammatory Diseases 01/2016 - 01/2014
4	Myocardial Infarction 05/2015 - 08/2005
3	Alzheimer Disease (Alzheimer's Disease) 01/2016 - 03/2009
3	Inflammation (Inflammations) 01/2016 - 04/2008
3	Infarction (Infarctions) 09/2013 - 11/2007
3	Hepatic Infarction 01/2011 - 11/2007
2	Pulmonary Arterial Hypertension 12/2017 - 02/2014
2	Residual Neoplasm 12/2013 - 01/2013
2	Body Weight (Weight, Body) 08/2013 - 12/2012
2	Pain (Aches) 04/2013 - 01/2013
2	Neurogenic Inflammation 04/2013 - 01/2013
2	Rhabdomyosarcoma 09/2011 - 05/2006
2	Parkinson Disease (Parkinson's Disease) 04/2010 - 03/2006
1	Carcinoma (Carcinomatosis) 12/2017
1	Cardiomyopathies (Cardiomyopathy) 12/2017
1	Schizophrenia (Dementia Praecox) 01/2017
1	Heart Failure 02/2014
1	Gallstones (Gallstone) 12/2013
1	Acute Kidney Injury (Acute Renal Failure) 01/2013
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2013
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2013
1	Renal Insufficiency (Renal Failure) 01/2013
1	Myocardial Ischemia (Ischemic Heart Diseases) 12/2012
1	Lung Neoplasms (Lung Cancer) 03/2012
1	Lymphoma (Lymphomas) 03/2012
1	Brain Neoplasms (Brain Tumor) 03/2012
1	Acidosis 01/2012
1	Hyperglycemia 01/2012
1	Central Nervous System Diseases (CNS Diseases) 07/2011
1	Atherosclerotic Plaque (Atheroma) 04/2008

Drug/Important Bio-Agent (IBA)

16	hypericinIBA 05/2015 - 12/2003
5	iodohydroxybenzylpindololIBA 05/2015 - 12/2012
5	Contrast MediaIBA 05/2006 - 05/2002
4	Biological ProductsIBA 12/2013 - 11/2007
4	Pentetic Acid (DTPA)FDA LinkGeneric 06/2013 - 11/2007
4	fosbretabulin (combretastatin A4)IBA 02/2013 - 09/2011
4	Ethanol (Ethyl Alcohol)IBA 01/2011 - 07/2007
3	Radioisotopes (Radionuclides)IBA 12/2017 - 07/2010
3	Pharmaceutical PreparationsIBA 01/2016 - 10/2012
3	RadiopharmaceuticalsIBA 01/2013 - 06/2009
3	pamoic acidIBA 07/2010 - 11/2007
2	Guanosine Monophosphate (5' Guanylic Acid)IBA 12/2017 - 02/2014
2	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 12/2017 - 02/2014
2	LipopolysaccharidesIBA 01/2016 - 10/2015
2	N,N- diethyl- 2- (2- (4- (2- fluoroethoxy)phenyl)- 5,7- dimethylpyrazolo(1,5- a)pyrimidin- 3- yl)acetamideIBA 01/2016 - 10/2015
2	LigandsIBA 01/2016 - 04/2007
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 02/2014 - 08/2013
2	Iodine-131IBA 01/2014 - 12/2013
2	Iodine-123IBA 01/2014 - 01/2012
2	CationsIBA 04/2013 - 01/2013
2	IodineIBA 07/2012 - 09/2011
2	SolutionsIBA 09/2011 - 03/2006
2	AcidsIBA 06/2009 - 07/2007
2	AlbuminsIBA 08/2005 - 05/2005
1	Fluorine-18IBA 12/2017
1	AntibodiesIBA 12/2017
1	Trastuzumab (Herceptin)FDA Link 12/2017
1	metabotropic glutamate receptor 2IBA 01/2017
1	CB2 Cannabinoid ReceptorIBA 01/2016
1	Purinergic P2X7 ReceptorsIBA 01/2016
1	EndocannabinoidsIBA 01/2016
1	Sodium CholateIBA 05/2015
1	Antineoplastic Agents (Antineoplastics)IBA 03/2014
1	Proteins (Proteins, Gene)FDA Link 01/2014
1	CholesterolIBA 12/2013
1	2- oxo- 7- methoxy- 8- butyloxy- 1,2- dihydroquinoline- 3- carboxylic acid cyclohexylamideIBA 08/2013
1	1,3,4,6-tetrachloro-3 alpha,6 alpha-diphenylglycolurilIBA 08/2013
1	indoleIBA 06/2013
1	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 06/2013
1	Biomarkers (Surrogate Marker)IBA 02/2013
1	TRPV1 receptorIBA 01/2013
1	Peptide Receptors (Peptide Receptor)IBA 01/2013
1	TubulinIBA 01/2013
1	AntigensIBA 10/2012
1	Peptides (Polypeptides)IBA 10/2012
1	3-Iodobenzylguanidine (Iobenguane)IBA 01/2012
1	malonic acid (malonate)IBA 01/2012
1	Gallium-68IBA 07/2010
1	HydrazinesIBA 07/2010
1	Oxidopamine (6 Hydroxydopamine)IBA 04/2010
1	nucleotide pyrophosphataseIBA 11/2009
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 11/2009
1	lysophosphatidic acidIBA 11/2009
1	alkylglycerophosphoethanolamine phosphodiesteraseIBA 11/2009
1	Amyloid beta-PeptidesIBA 03/2009
1	gadolinium-DTPA-g-mimRGDIBA 04/2008
1	Gadolinium DTPA (Magnevist)FDA Link 04/2008
1	Integrin alphaVIBA 04/2008
1	Integrin beta3 (GPIIIa)IBA 04/2008

Therapy/Procedure

10	Therapeutics 01/2017 - 08/2005
6	Radiotherapy 02/2014 - 04/2011
3	Intravenous Injections 12/2013 - 05/2007
3	Precision Medicine 01/2013 - 01/2012
2	Aftercare (After-Treatment) 09/2011 - 04/2011
1	Catheters 12/2013
1	Injections 07/2012
1	Cell- and Tissue-Based Therapy (Cell Therapy) 07/2011
1	Drug Therapy (Chemotherapy) 04/2011